Varicella-zoster Virus: Genetics, Pathogenesis and Immunity (Current Topics in Microbiology and Immunology, 438)

Varicella-zoster Virus: Genetics, Pathogenesis and Immunity (Current Topics in Microbiology and Immunology, 438)

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Varicella-zoster Virus: Genetics, Pathogenesis and Immunity (Current Topics in Microbiology and Immunology, 438)

By Ann M. Arvin, Jennifer F. Moffat, Allison Abendroth, Stefan L Oliver
This edited volume provides insights about the molecular virology, pathoenesis of infection and host responses to varicella-zoster virus, which is a medically important human herpesvirus.  The chapters not only discuss genetics and molecular evolution of the virus, but also new structure-based knowledge on the functions of viral glycoproteins. Further, the authors illustrate how mechanisms from the virus are used to take over and remodel host cells during pathogeneis. These mechanisms also enable viral modulation of host cells and evasion of the host immune response. Part of these evasion and survival strategies, is the reaction to triggered host cell responses like autophagy, the stress response, modulation of apoptosis and other cell death pathways. This hands-on knowledge is crucial for students and clinicians in Virology, Immunology, and Infectious Diseases.Chapter “Common features between stroke following varicella in children and stroke following herpes zoster in adults” is available open access under a Creative Commons Attribution 4.0 International License via Springerlink.com.

The book “Varicella-Zoster Virus: Molecular Virology, Pathogenesis, and Host Response” is an essential resource for anyone interested in the field of virology, immunology, and infectious diseases. Written by Ann M. Arvin, Jennifer F. Moffat, Allison Abendroth, and Stefan L Oliver, this edited volume provides comprehensive insights into the genetic and molecular aspects of the varicella-zoster virus (VZV), also known as human herpesvirus 3.

The book delves into the molecular virology of VZV, exploring its genetic composition, evolution, and structure-based knowledge of viral glycoproteins. It also sheds light on the pathogenesis of VZV infection and the complex host responses triggered by the virus. The authors discuss in detail how VZV remodels host cells during infection and the mechanisms it employs to evade the host immune response. Additionally, the book explores the interaction between VZV and various host cell responses, including autophagy, stress response, apoptosis, and other cell death pathways.

One of the standout chapters in the book is “Common features between stroke following varicella in children and stroke following herpes zoster in adults.” This chapter, available open access, uncovers the commonalities between the occurrence of stroke in children with varicella and adults with herpes zoster. The insights provided in this chapter can contribute significantly to our understanding of the neurological complications associated with VZV infection.

With its comprehensive coverage and up-to-date research, “Varicella-Zoster Virus: Molecular Virology, Pathogenesis, and Host Response” is an invaluable resource for both students and clinicians. Whether you are studying virology, immunology, or infectious diseases, this book offers hands-on knowledge that is crucial for understanding the complexities of VZV infection and its impact on the human body.

About the Authors

The book is authored by a team of renowned experts in the field of virology and infectious diseases. Ann M. Arvin is a Professor of Pediatrics and Microbiology & Immunology at Stanford University School of Medicine. Jennifer F. Moffat is a Senior Research Associate in the Department of Pediatrics at Stanford University School of Medicine. Allison Abendroth is a Senior Research Associate at Stanford School of Medicine. Stefan L Oliver is an Associate Professor in the Department of Pediatrics at Stanford University School of Medicine. Their collective expertise and extensive research experience make this book a reliable and authoritative source of information.

Product Details

  • Publisher: Springer; 1st ed. 2023 edition (November 2, 2022)
  • Language: English
  • Format: eBook, Digital
  • Pages: 280
  • ISBN-10: 3031153049
  • ISBN-13: 978-3031153044

Why You Should Order this Book

If you are a student or a clinician looking to expand your knowledge in virology, immunology, or infectious diseases, “Varicella-Zoster Virus: Molecular Virology, Pathogenesis, and Host Response” is a must-have resource. This book goes beyond mere textbook knowledge and provides in-depth insights into the molecular mechanisms of the varicella-zoster virus and its interaction with the host. By reading this book, you will gain a thorough understanding of the genetic composition, evolution, and structure of the virus, as well as its pathogenesis and impact on host cells. Furthermore, you will learn about the strategies employed by the virus to evade the host immune response, enhancing your understanding of viral immune evasion mechanisms.

With its detailed exploration of various host cell responses triggered by VZV infection, such as autophagy, stress response, apoptosis, and cell death pathways, this book provides a comprehensive view of the complex interactions between the virus and the host. These insights can have significant implications for the development of antiviral therapies and vaccines.

Order “Varicella-Zoster Virus: Molecular Virology, Pathogenesis, and Host Response” today and embark on a comprehensive journey into the world of VZV. As you delve into the pages of this book, you will gain a deep understanding of the virus and its impact on the human body. Whether you are a student or a clinician, this book is an essential addition to your library.

Product Details

  • Publisher ‏ : ‎ Springer; 1st ed. 2023 edition (November 2, 2022)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 280 pages
  • ISBN-10 ‏ : ‎3031153049
  • ISBN-13 ‏ : ‎ 978-3031153044

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