Prions and Diseases, 2nd Edition
Transmissible spongiform encephalopathies (TSE), known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including the protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains by far the most authoritative views about the past, present, and future of prions and prion diseases. The new second edition covers such important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
Product Details
- Publisher: Springer International Publishing; January 1, 2023
- Language: English
- ISBN: 9783031205644
- ISBN: 9783031205651
The second edition of Prions and Diseases, written by Wen-Quan Zou, is a comprehensive and up-to-date resource that delves into the world of prion diseases. Prions, also known as transmissible spongiform encephalopathies (TSE), have been recognized for centuries and continue to captivate scientists and researchers due to their unique infectious properties and devastating impact on both animals and humans.
Prions are infectious protein particles that can cause the misfolding of normal proteins, leading to the formation of toxic aggregates in the brain. This abnormal protein accumulation ultimately results in the degeneration and destruction of brain tissue, leading to a wide range of neurological symptoms and, in many cases, fatal outcomes. The study of prion diseases has significantly advanced in recent years, thanks to techniques such as protein-misfolding cyclic amplification (PMCA) and the contributions of dedicated researchers.
In Prions and Diseases, Wen-Quan Zou brings together more than 60 leading researchers and clinicians from around the world to provide a comprehensive and authoritative account of prion diseases. The book covers the etiology, pathogenesis, classification, histopathological, and clinical aspects of both animal and human prion diseases. By encompassing a broad range of topics, the book offers a complete understanding of prion diseases, making it an invaluable resource for researchers, clinicians, and students in the field.
One of the standout features of this second edition is its coverage of emerging topics and advancements in prion research. The book explores areas such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies. These cutting-edge topics highlight the current developments in the field and provide insights into future directions for research and therapeutic approaches.
Prions and Diseases not only presents the latest scientific knowledge but also discusses the historical context and future perspectives of prion diseases. By providing an overview of the past, present, and future of prions, the book ensures readers have a well-rounded understanding of these complex diseases.
Readers will find that Prions and Diseases is written in a clear and accessible manner, making it suitable for a wide range of audiences. The book is a valuable resource for researchers looking to expand their knowledge of prion diseases, clinicians seeking the latest information to inform their practice, and students interested in delving into this fascinating field of study.
Order your copy of Prions and Diseases today and immerse yourself in the captivating world of prion research. This book is a must-have for anyone interested in understanding the intricacies of these unique infectious pathogens and their associated diseases. With its comprehensive coverage and contributions from leading experts, this second edition is sure to become a staple in the field of prion research.
Product Details
- Publisher: Springer International Publishing; January 1, 2023
- Language: English
- ISBN: 9783031205644
- ISBN: 9783031205651