Thymic Development and Selection of T Lymphocytes (Current Topics in Microbiology and Immunology) 2014th Edition

Thymic Development and Selection of T Lymphocytes (Current Topics in Microbiology and Immunology) 2014th Edition

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by Thomas Boehm

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    Thymic Development and Selection of T Lymphocytes (Current Topics in Microbiology and Immunology) 2014th Edition

    by Thomas Boehm

    The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.

     

    Product details

    • Series: Current Topics in Microbiology and Immunology (Book 373)
    • Hardcover: 132 pages
    • Publisher: Springer; 2014 edition (November 7, 2013)
    • Language: English
      • Type : PDF 

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