Pi3k and Akt Isoforms in Immunity: Mechanisms and Therapeutic Opportunities: 436

Pi3k and Akt Isoforms in Immunity: Mechanisms and Therapeutic Opportunities: 436

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Pi3k and Akt Isoforms in Immunity: Mechanisms and Therapeutic Opportunities: 436

By Margarita Dominguez-Villar

By Margarita Dominguez-Villar

This book provides an essential overview of the role of phosphoinositide-3-phosphate kinase (PI3K) isoforms in modulating the function of immune system cells and their involvement in disease.

PI3K is a family of kinases involved in basic cellular processes such as proliferation, migration, and cell death. Recent work has highlighted the multiple roles of PI3K classes and subunits and their involvement in the immune response to the body’s own and foreign antigens and diseases such as cancer and autoimmunity. Understanding the role of PI3K isoforms is crucial for developing new therapeutic strategies to target immune-mediated diseases.

In this comprehensive book, Margarita Dominguez-Villar delves into the biology of the three PI3K classes, providing a detailed introduction to each class and their diverse roles in immune cells. The book starts by offering a solid foundation of knowledge on the structure, regulation, and function of PI3K isoforms. It discusses the signaling pathways involved, particularly the role of AKT and other downstream effectors in immune cell activation and function.

One of the key strengths of this book is its focus on the connection between PI3K isoforms and immune-mediated diseases. Dominguez-Villar explores the latest scientific findings on the involvement of specific PI3K isoforms in diseases such as cancer, autoimmune disorders, and immunodeficiencies. By elucidating the molecular mechanisms underlying these diseases, the author not only provides a valuable resource for researchers and students but also presents potential therapeutic targets for drug development.

The book also highlights the latest advances in the production of isoform-specific inhibitors and their use in various human diseases. This section showcases the cutting-edge research that is paving the way for personalized medicine, where the specific isoform involved in a disease can be targeted with precision.

Throughout the book, Dominguez-Villar presents complex scientific concepts in a clear and accessible manner. The content is well-organized and supported by illustrative figures and tables, making it easy for readers to grasp the intricate details of PI3K biology and its role in immunology.

Overall, “PI3K Isoforms in Immune Cells and Diseases” serves as an exceptional reference guide for students, researchers, and medical professionals interested in unraveling the diverse roles of PI3K isoforms in immune system function and disease pathogenesis. From the biology of PI3K classes to their involvement in specific diseases, this book provides a comprehensive overview of this rapidly evolving field.

Order your copy of “PI3K Isoforms in Immune Cells and Diseases” today and embark on a journey through the intricate world of PI3K biology. Gain a deeper understanding of how these enzymes modulate immune cell function and their potential as therapeutic targets for a wide range of diseases. Whether you are a student, researcher, or medical professional, this book will undoubtedly expand your knowledge and inspire new avenues of investigation in the field of immunology.

Product Details

  • Editorial ‏ : ‎ Springer; Edición 2022 ed. (16 octubre 2022)
  • Idioma ‏ : ‎ Inglés
  • Pasta dura ‏ : ‎ 466 páginas
  • ISBN-10 ‏ : ‎ 3031065654
  • ISBN-13 ‏ : ‎ 978-3031065651
  • Dimensiones ‏ : ‎ 15.6 x 2.69 x 23.39 cm

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