Normal Cytology

Normal Cytology

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File Size : 30.3 MB

Category:

Normal Cytology

by Madelyn Lew (Author)

In the practice of cytopathology, cytologists frequently encounter a spectrum of benign, normal cells in samples. In fact, these normal cells frequently comprise the greatest proportion of material present on a cytology slide. This is frequently the case in Pap smears of the uterine cervix , urine samples, and lung samples such as bronchial brushings. Normal cytology can often mimic pathology leading to misdiagnoses, especially in cases with reactive and metaplastic changes. Moreover, cytopathology findings of certain neoplasms can also mimic normal cytology.
Today, cytology laboratories are no longer confined to dealing with just exfoliative specimens and superficial aspirations. With interventional radiology as well as endobronchial and endoscopic ultrasound-guided fine needle aspirations (FNA), we increasingly encounter visceral samples. Hence, cytologists are even likely to encounter normal elements from deep-seated organs. Sometimes, unexpected normal elements may be found within cytology specimens because a FNA procedure has contamination or inadvertently sampled a nearby organ or normal anatomical structure. A typical example is the finding of ganglion cells when a FNA is performed targeting a celiac node for cancer staging (Elgarby EA et al. Frequency and characterization of celiac ganglia diagnosed on fine-needle aspiration. Cytojournal. 2015; 12:4). 
Despite the importance of knowing the spectrum of normal cytology, there are limited reference materials available on this topic for cytologists. Most cytopathology texts deal with abnormal cytology. Often, the chapters in these books only devote a few sentences about normal cytology (euplasia). Our proposed book intends to fulfil this need. The book will contain a mixture of text and images (atlas). Important aspects related to cytology practice will be highlighted such as clinical relevance, differential diagnoses, mimics and pitfalls. The images will include a variety of cytology specimen preparations (e.g. direct smears, liquid based samples, touch preparations, cell blocks) and stains (e.g. Diff Quik/MGG, Papanicolaou, H&E). In selected cases, the expected immunoprofile of normal cells will be addressed. Each chapter will also include a modest list of helpful and contemporary references.

Product Details

  • Publisher: Springer International Publishing; January 1, 2023
  • Language: English
  • ISBN: 9783031203350
  • ISBN: 9783031203367

Introducing “Normal Cytology: A Comprehensive Guide” by Madelyn Lew. In this groundbreaking book, Dr. Lew provides cytologists with a comprehensive reference on normal cytology, filling a major gap in the field. While most cytopathology texts focus on abnormal cytology, this book delves into the spectrum of benign, normal cells frequently encountered in cytology samples.

Cytologists often encounter normal cells in samples, making up the majority of material on a cytology slide. However, these normal cells can sometimes mimic pathology, leading to misdiagnoses. This is especially true in cases with reactive and metaplastic changes. Additionally, cytopathology findings of certain neoplasms can also mimic normal cytology. With the increase in deep-seated organ samples through interventional radiology and ultrasound-guided aspirations, cytologists are likely to encounter normal elements from various organs. Unexpected normal elements may also be found due to contamination or inadvertently sampling a nearby organ or structure.

Despite the importance of understanding normal cytology, there are few reference materials available on this topic for cytologists. This book aims to fill this need by providing a mixture of text and images. Important aspects related to cytology practice, such as clinical relevance, differential diagnoses, mimics, and pitfalls, will be highlighted. The book will include a variety of cytology specimen preparations, such as direct smears, liquid-based samples, touch preparations, and cell blocks. Stains like Diff Quik/MGG, Papanicolaou, and H&E will be used. In certain cases, the expected immunoprofile of normal cells will also be addressed. Each chapter includes a modest list of helpful and contemporary references.

By diving deep into the topic of normal cytology, “Normal Cytology: A Comprehensive Guide” equips cytologists with the knowledge and tools to accurately identify and differentiate between normal and abnormal cells. The text is accompanied by a rich atlas of images, providing visual examples of normal cytology in various sample preparations and stains.

Whether you are a cytologist, pathologist, or medical student, this book is an essential resource for understanding and diagnosing cytology samples. Dr. Lew’s expertise and comprehensive approach make “Normal Cytology: A Comprehensive Guide” a must-have reference in the field.

Order your copy of “Normal Cytology: A Comprehensive Guide” today and enhance your cytology practice with a thorough understanding of normal cytology. Expand your knowledge, enhance your diagnostic abilities, and improve patient outcomes with this invaluable resource.

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