Mammalian Heme Peroxidases : Diverse Roles in Health and Disease
Are you interested in exploring the fascinating world of mammalian heme peroxidase enzymes and their role in both innate immunity and chronic inflammatory diseases? Look no further because “Mammalian Heme Peroxidases: Chemistry, Biochemistry, and Pathological Implications” by Clare Hawkins delves deep into the chemistry, biochemistry, and biological roles of these enzymes. Whether you are a medical professional, researcher, or simply curious about the inner workings of the human body, this book offers valuable insights into this important field of study.
Understanding the Role of Mammalian Heme Peroxidases
Mammalian heme peroxidase enzymes play a critical role in our body’s innate immune responses and disease prevention. These enzymes are responsible for the formation of potent chemical oxidants, which are essential for our protective physiological activity in immunity. However, while they are beneficial in defending against pathogens, it has been established that the overproduction of oxidants by peroxidases contributes to the initiation and persistence of various chronic inflammatory conditions in different organ systems.
In addition to heme peroxidases, this book also explores the role of peroxidasins, a related protein family, in tissue biogenesis and matrix assembly. These peroxidasins have gained attention in different pathological contexts and provide a novel perspective on tissue development.
Recent Developments and Potential Therapeutic Approaches
Given the wide-ranging roles of mammalian heme peroxidases and the incidence of pathologies associated with these enzymes, there is significant interest in modulating peroxidase activity as a therapeutic strategy. “Mammalian Heme Peroxidases: Chemistry, Biochemistry, and Pathological Implications” highlights the recent developments in our understanding of these enzymes and their associated oxidants. It explores topics such as the structure and biosynthesis of mammalian peroxidases, the reactivity of hypohalous acids with biological substrates, peroxidases in innate immunity, peroxidases in human pathology, and the modulation of peroxidase-induced biological damage.
Expert Knowledge and Comprehensive Coverage
Written by Clare Hawkins, an expert in the field, this book combines scientific rigor with a comprehensive yet accessible writing style. It presents the latest research findings and insights in a way that is digestible for both professionals and those new to the subject. The book is divided into clear sections, allowing readers to delve into specific topics of interest or explore the entire breadth of mammalian heme peroxidase research.
Hawkins provides a detailed examination of the structure and biosynthesis of mammalian peroxidases, shedding light on their intricate mechanisms and how they contribute to innate immunity. The reactivity of hypohalous acids with biological substrates is thoroughly explored, giving readers a deeper understanding of the chemical reactions involved in peroxidase activity.
The book also delves into the role of peroxidases in human pathology, exploring how their overproduction of oxidants contributes to chronic inflammatory conditions in various organ systems such as the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. By elucidating these connections, Hawkins equips readers with the knowledge needed to tackle these pathologies and potentially develop therapeutic interventions.
Order Your Copy and Dive Into the World of Mammalian Heme Peroxidases
Ready to embark on a journey into the fascinating world of mammalian heme peroxidases? “Mammalian Heme Peroxidases: Chemistry, Biochemistry, and Pathological Implications” is a must-have resource for anyone interested in understanding the intricate workings of our immune system and its connection to chronic inflammatory diseases. Order your copy today and delve into the cutting-edge research and potential therapeutic approaches presented in this comprehensive book.
Product Details
- Structure and biosynthesis of mammalian peroxidases
- Reactivity of hypohalous acids with biological substrates
- Peroxidases in innate immunity
- Peroxidases in human pathology
- Modulation of peroxidase-induced biological damage
- Publisher: CRC Press; October 8, 2021
- Language: English
- ISBN: 9780367820367
- ISBN: 9781000450613
- eText ISBN: 9781003212287
- eText ISBN: 9781000450637