Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1

Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1

6 $

Format : Publisher PDF

File Size : 6.1 MB

Category:

Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1

by Nima Rezaei (Author)

Brain tumors are a significant health concern, accounting for about 5-9% of all human neoplasms. What makes them even more alarming is that central nervous system (CNS) tumors are among the most prevalent neoplasms in children. These tumors have specific molecular characteristics and pathways that play a crucial role in their development and progression. Understanding these molecular aspects is essential for developing effective therapeutic approaches.

In his groundbreaking book, “Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics,” author Nima Rezaei delves into the intricate world of brain and spinal cord tumors. Rather than focusing solely on morphological and histopathological characteristics, Rezaei explores the molecular classification of tumors as a crucial aspect for determining the most appropriate therapeutic interventions.

One of the key challenges in treating brain tumors lies in their ability to evade the immune system. Tumors have complex mechanisms in place to prevent the immune system from eliminating them, leading to tumor development and progression. Rezaei recognizes the importance of the neuro-immunologic mechanism in the development of psychiatric manifestations of brain tumors. By understanding the intricate relationship between the immune system and tumors, researchers and clinicians can develop immunotherapeutic approaches to bolster the weakened immune system’s ability to combat tumors.

Rezaei explores various immunotherapeutic approaches, including dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy. Each of these approaches aims to activate or strengthen the anti-tumor immune response, providing new hope for patients battling brain and spinal cord tumors.

In addition to the immunologic components, Rezaei sheds light on the genetic pathways that contribute to the development of brain and spinal cord tumors. By uncovering non-immune genetic pathways, Rezaei opens the door to novel therapeutic approaches, such as stem cell therapy and gene therapy. These groundbreaking treatments hold immense potential for revolutionizing cancer treatment in the new era of precision medicine.

The book also explores physical and mathematical models that help explain and predict tumor behavior. These models provide crucial insights into tumor biology and aid in the development of new therapeutic modalities in pre-clinical stages. By combining the fields of genetics, immunology, and mathematical modeling, Rezaei offers a comprehensive approach to understanding and treating brain and spinal cord tumors.

“Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics” is a valuable resource for experts in basic sciences, including geneticists and immunologists, as well as physicians from various specialties, such as neurosurgeons, neurologists, neuropathologists, and neuroradiologists. The book’s interdisciplinary approach ensures a comprehensive understanding of the complexities of brain and spinal cord tumors.

Product Details

  • Publisher: Springer International Publishing; January 1, 2023
  • Language: English
  • ISBN: 9783031147319
  • ISBN: 9783031147326

Order your copy of “Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics” today and embark on a journey of discovery into the molecular, immunologic, and genetic aspects of these tumors. Gain invaluable insights that will shape the future of cancer treatment and contribute to the fight against brain and spinal cord tumors.

Product Details

  • Publisher: Springer International Publishing; January 1, 2023
  • Language: English
  • ISBN: 9783031147319
  • ISBN: 9783031147326

Related Products