HLA and Disease, An Issue of the Clinics in Laboratory Medicine (Volume 38-4)

HLA and Disease, An Issue of the Clinics in Laboratory Medicine (Volume 38-4)

12 $

Format : Publisher PDF

File Size : 8.5 MB

Category:

HLA and Disease, An Issue of the Clinics in Laboratory Medicine (Volume 38-4)

By Julio Delgado, Eszter Lazar-Molnar
This issue of Clinics in Laboratory Medicine, edited by Drs. Julio Delgado and Eszter Lazar-Molnar, will focus on HLA and Disease. Topics include, but are not limited to, The potential impact of NGS in HLA and disease association studies, HLA typing by NGS, HLA Antibody Testing: Evolution and Challenges, Diversity of killer cell immunoglobulin-like receptors and disease, Technical Aspects of Crossmatching in Transplantation, HLA Markers in Celiac Disease, HLA Associations in Drug Hypersensitivity Reactions, HLA in BMT, Post-transplant monitoring, HLA epitope matching in transplantation, and Molecular Testing in Post-Transplant Monitoring.

By Julio Delgado, Eszter Lazar-Molnar
This issue of Clinics in Laboratory Medicine, edited by Drs. Julio Delgado and Eszter Lazar-Molnar, focuses on the intricate relationship between Human Leukocyte Antigen (HLA) and disease. With the advent of Next Generation Sequencing (NGS) technology, researchers are now able to delve deeper into the complexities of the HLA system, shedding light on its crucial role in disease susceptibility, progression, and therapeutic interventions. This comprehensive collection of articles from leading experts in the field explores various aspects of HLA and Disease, providing insights into the potential impact of NGS in HLA and disease association studies, HLA typing by NGS, and the evolving challenges in HLA antibody testing.

One of the key areas of focus in this issue is the diversity of killer cell immunoglobulin-like receptors (KIRs) and their association with disease. These receptors play a vital role in immune surveillance and response, and their aberrant expression or function has been implicated in various diseases, including cancer, autoimmune disorders, and infectious diseases. The articles in this volume delve into the current understanding of KIR diversity and its implications in disease pathology, diagnosis, and therapeutics.

Transplantation is another crucial area where HLA plays a pivotal role. The technical aspects of crossmatching in transplantation are explored in detail, along with the HLA markers associated with celiac disease and drug hypersensitivity reactions. The use of HLA epitope matching in transplantation and the role of HLA in bone marrow transplantation are also discussed. Additionally, the issue covers the importance of HLA in post-transplant monitoring and highlights the role of molecular testing in this context.

This book is a valuable resource for researchers, clinicians, and laboratory professionals who are involved in HLA and disease association studies, transplantation medicine, and post-transplant monitoring. The comprehensive review of the current knowledge and advancements in the field provides a solid foundation for understanding the intricate relationship between HLA and disease, paving the way for future research and therapeutic interventions.

Product Details

  • Publisher: Elsevier; 1st edition (7 December 2018)
  • Language: English
  • ISBN-10: 0323642209
  • ISBN-13: 978-0323642200

Order your copy of “HLA and Disease” today and explore the intriguing world of HLA and its impact on disease susceptibility, diagnosis, and therapeutics. This comprehensive volume is a must-have for anyone interested in the complexities of the HLA system and its implications in various diseases. Gain valuable insights from leading experts in the field and stay updated with the latest advancements in HLA research.

Product Details

  • Publisher ‏ : ‎ Elsevier; 1st edition (7 December 2018)
  • Language ‏ : ‎ English
  • ISBN-10 ‏ : ‎ 0323642209
  • ISBN-13 ‏ : ‎ 978-0323642200

Related Products